MCM is a rare, complex disorder of the skin and other organs that is present at birth (congenital) Affected individuals have a disproportionately large head and pinktored lacy patches (vascular malformations) on the skin of the trunk, limbs and middle portion of the faceMegalencephalycapillary malformation syndrome (MCAP) is a disorder characterized by overgrowth of several tissues in the body Its primary features are a large brain (megalencephaly) and abnormalities of small blood vessels in the skin called capillaries (capillary malformations) In individuals with MCAP, megalencephaly leads to an unusually large head size ( macrocephaly ),Millon & Davis, 1996) The scales and profiles of the MCMI thus measure these theoryderived and theoryrefined variables directly and quantifiably
3 M Syndrome Medlineplus Genetics
